Across TCGA pan-cancer cohorts, LGALS7 Mutation is linked to patient survival in 2 of 34 cancer types, making it a survival-associated LGALS7 data layer compared with 21 for mass-spec protein.

The strongest signal is observed in uterine carcinosarcoma (UCS), where higher LGALS7 Mutation is associated with worse disease-free survival. In most high-consensus cancer types, elevated LGALS7 expression acts as an unfavorable survival marker.

UCS and ACC are the cancer types where LGALS7 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCS	DFS	Median	All	0.068	0.524	<.001	48	view →
ACC	DFS	Median	All	0.195	0.748	.003	3	view →

Pink = unfavorable, green = favorable. Showing the 2 strongest of 2 lineages.

Exploration

Same gene, other analysis: LGALS7 tumor-vs-normal RNA expression · all LGALS7 data types