LGALS7

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, LGALS7 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,962 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible LGALS7-associated GO terms across cancer lineages are Keratinization, Regulation of skeletal muscle tissue regeneration, and Autocrine signaling. Each is linked with LGALS7 in more than 10 cancer types. Because this analysis shows association rather than direction, both LGALS7-to-partner and partner-to-LGALS7 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (LGALS7→partner) and Y-score (partner→LGALS7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
ESCAKeratinization →+0.208+3.665<.001<.001311
ESCARegulation of skeletal muscle tissue regeneration →+0.271+4.492<.001<.001311
ESCAAutocrine signaling →+0.127+3.388<.001<.001310
ESCAPositive regulation of keratinocyte proliferation →+0.109+2.757<.001<.001310
ESCASkin epidermis development →+0.041+1.991<.001<.00139
ESCAEstablishment of skin barrier →+0.061+1.663<.001<.00139
Each partner links to its Q-omics profile. Showing the 6 strongest of 5,962 associations by consensus.

Exploration