LGALS7

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → FUNCTION-RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, LGALS7 protein abundance is significantly associated with the go_rna of many other GO terms, with 458 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible LGALS7-associated GO terms across cancer lineages are Positive regulation of interleukin-18-mediated signaling pathway, Hypersensitivity, and Cytotoxic T cell degranulation. Each is linked with LGALS7 in more than 2 cancer types. Because this analysis shows association rather than direction, both LGALS7-to-partner and partner-to-LGALS7 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (LGALS7→partner) and Y-score (partner→LGALS7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
STOMACHPositive regulation of interleukin-18-mediated signaling pathway →-2.106-3.960.001.00823
LUNG_NSCLC_LUADHypersensitivity →-0.382-3.483.005<.00132
LUNG_NSCLC_LUADCytotoxic T cell degranulation →-0.429-3.849<.001<.00132
LUNG_NSCLC_LUADSensory perception of sweet taste →-0.192-3.483.006<.00132
LUNG_NSCLC_LUADSensory perception of umami taste →-0.170-3.483.006<.00132
LUNG_NSCLC_LUADCardiac vascular smooth muscle cell differentiation →-0.295-3.483.003<.00132
Each partner links to its Q-omics profile. Showing the 6 strongest of 458 associations by consensus.

Exploration