LGALS3BP

Across TCGA patient cohorts, LGALS3BP mutation is significantly associated with the total protein of many other genes, with 3 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible LGALS3BP-associated genes across cancer lineages are Notch1, eIF4E, and MEK1. Each is linked with LGALS3BP in more than 1 cancer types. Because this analysis shows association rather than direction, both LGALS3BP-to-partner and partner-to-LGALS3BP results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Notch1 grouped by LGALS3BP-low versus LGALS3BP-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LGALS3BP→partner) and Y-score (partner→LGALS3BP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Notch1 →	+0.115	+1.584	.038	.036	3	2
UCEC	eIF4E →	+0.173	+3.013	.037	.018	3	1
UCEC	MEK1 →	+0.313	+2.459	.029	.019	3	1

Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

Notch1 by LGALS3BP expression — UCEC

Explore this box plot interactively →