LGALS3BP

Across TCGA cell cohorts, LGALS3BP RNA expression is significantly associated with the go_rna of many other GO terms, with 4,896 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible LGALS3BP-associated GO terms across cancer lineages are Viral protein processing, Negative regulation of regulatory T cell differentiation, and Negative regulation of IP-10 production. Each is linked with LGALS3BP in more than 12 cancer types. Because this analysis shows association rather than direction, both LGALS3BP-to-partner and partner-to-LGALS3BP results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Viral protein processing grouped by LGALS3BP-low versus LGALS3BP-high in CNS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (LGALS3BP→partner) and Y-score (partner→LGALS3BP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CNS	Viral protein processing →	+0.121	+2.327	<.001	<.001	3	13
PANCREAS	Negative regulation of regulatory T cell differentiation →	+0.163	+1.228	<.001	.001	3	12
SOFT_TISSUE	Negative regulation of IP-10 production →	+1.161	+2.893	<.001	<.001	3	11
SOFT_TISSUE	Maintenance of protein localization in organelle →	+0.117	+2.429	<.001	<.001	3	11
CNS	Negative regulation of mast cell degranulation →	+1.721	+2.278	<.001	<.001	3	11
BREAST	Regulation of viral process →	+0.132	+3.197	<.001	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,896 associations by consensus.

Viral protein processing by LGALS3BP expression — CNS

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