LGALS3BP

Across TCGA cell cohorts, LGALS3BP mutation is significantly associated with the drug of many other genes, with 8 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible LGALS3BP-associated genes across cancer lineages are GSK2110183B, Sabutoclax, and PF-00299804. Each is linked with LGALS3BP in more than 1 cancer types. Because this analysis shows association rather than direction, both LGALS3BP-to-partner and partner-to-LGALS3BP results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, GSK2110183B grouped by LGALS3BP-low versus LGALS3BP-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LGALS3BP→partner) and Y-score (partner→LGALS3BP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	GSK2110183B →	+0.682	+2.871	.017	.021	3	1
LARGE_INTESTINE	Sabutoclax →	+0.449	+2.991	.025	.018	3	1
LARGE_INTESTINE	PF-00299804 →	+0.622	+2.874	.004	.021	3	1
LARGE_INTESTINE	SGC0946 →	+0.293	+2.710	.040	.043	2	1
LARGE_INTESTINE	GSK3337463A →	+0.386	+2.871	.016	.021	1	1
LARGE_INTESTINE	GSK2830371A →	+0.323	+2.871	.036	.021	1	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 8 associations by consensus.

GSK2110183B by LGALS3BP expression — LARGE_INTESTINE

Explore this box plot interactively →