LGALS3

mutation — cross-omics
Cross-omicsMUTATION → IMMUNEPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, LGALS3 mutation is significantly associated with the immune_cell of many other genes, with 1 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible LGALS3-associated genes across cancer lineages are Adipocytes. Each is linked with LGALS3 in more than 1 cancer types. Because this analysis shows association rather than direction, both LGALS3-to-partner and partner-to-LGALS3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Adipocytes grouped by LGALS3-low versus LGALS3-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LGALS3→partner) and Y-score (partner→LGALS3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECAdipocytes →+0.034+3.244.003.02031
Each partner links to its Q-omics profile. Showing the 1 strongest of 1 associations by consensus.

Adipocytes by LGALS3 expression — UCEC

Box plot of Adipocytes in LGALS3-low vs LGALS3-high samples in UCEC.

Explore this box plot interactively →

Exploration