LGALS3

Across TCGA cell cohorts, LGALS3 RNA expression is significantly associated with the RNA expression of many other genes, with 11,729 significant associations in total. BONE shows the largest number of these associations.

The most reproducible LGALS3-associated genes across cancer lineages are ANXA4, S100A6, and HNMT. Each is linked with LGALS3 in more than 8 cancer types. Because this analysis shows association rather than direction, both LGALS3-to-partner and partner-to-LGALS3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, LGALS3 versus ANXA4 in BLOOD_Lymphoma, with a Pearson correlation of 0.61.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LGALS3→partner) and Y-score (partner→LGALS3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	ANXA4 →	+2.077	+2.748	<.001	<.001	3	9
BONE	S100A6 →	+5.895	+5.246	<.001	<.001	3	9
LUNG_NSCLC_LUSC	HNMT →	+3.818	+4.331	<.001	<.001	3	8
STOMACH	MYO5B →	+2.516	+2.826	<.001	<.001	3	8
LUNG_SCLC	TMBIM1 →	+2.152	+2.628	<.001	<.001	3	8
BLOOD_Myeloma	SCML2 →	-2.163	-2.943	<.001	<.001	2	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,729 associations by consensus.

LGALS3 vs ANXA4 — BLOOD_Lymphoma

Explore this scatter interactively →