LGALS2

Across TCGA patient cohorts, LGALS2 RNA expression is significantly associated with the protein abundance of many other proteins, with 17,823 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible LGALS2-associated proteins across cancer lineages are ACAP1_T739, ARHGAP45_S578, and IL16. Each is linked with LGALS2 in more than 7 cancer types. Because this analysis shows association rather than direction, both LGALS2-to-partner and partner-to-LGALS2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, LGALS2 versus ACAP1_T739 in LSCC, with a Pearson correlation of 0.47.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (LGALS2→partner) and Y-score (partner→LGALS2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	ACAP1_T739 →	+0.978	+0.829	<.001	<.001	3	8
LSCC	ARHGAP45_S578 →	+0.716	+0.783	<.001	<.001	3	8
HNSC	IL16 →	+0.678	+0.985	<.001	<.001	3	8
OV	ANKRD44 →	+0.443	+1.139	<.001	<.001	3	7
HNSC	LCP2 →	+0.437	+0.734	<.001	<.001	3	7
BRCA	APOL3 →	+0.647	+0.971	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 17,823 associations by consensus.

LGALS2 vs ACAP1_T739 — LSCC

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