LGALS14

Across TCGA patient cohorts, LGALS14 protein abundance is significantly associated with the RNA expression of many other genes, with 15,037 significant associations in total. GBM shows the largest number of these associations.

The most reproducible LGALS14-associated genes across cancer lineages are AP3B2, CPEB1-AS1, and OTUD7A. Each is linked with LGALS14 in more than 8 cancer types. Because this analysis shows association rather than direction, both LGALS14-to-partner and partner-to-LGALS14 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, LGALS14 versus AP3B2 in LSCC, with a Pearson correlation of 0.77.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LGALS14→partner) and Y-score (partner→LGALS14) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	AP3B2 →	+0.968	+1.547	<.001	<.001	3	9
UCEC	CPEB1-AS1 →	+0.401	+1.048	.002	.001	3	8
GBM	OTUD7A →	+0.781	+0.669	<.001	<.001	3	7
LUAD	WDR17 →	+0.802	+0.938	.001	.005	3	6
HNSC	TMEM178B →	+1.024	+0.963	<.001	<.001	3	6
GBM	FXYD6 →	+1.640	+0.715	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,037 associations by consensus.

LGALS14 vs AP3B2 — LSCC

Explore this scatter interactively →