LGALS14

mutation — cross-omics
Cross-omicsMUTATION → PROTEIN-RPPAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, LGALS14 mutation is significantly associated with the total protein of many other genes, with 2 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible LGALS14-associated genes across cancer lineages are Cyclin-E2 and Ku80. Each is linked with LGALS14 in more than 1 cancer types. Because this analysis shows association rather than direction, both LGALS14-to-partner and partner-to-LGALS14 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Cyclin-E2 grouped by LGALS14-low versus LGALS14-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LGALS14→partner) and Y-score (partner→LGALS14) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECCyclin-E2 →+0.195+3.000.045.03732
UCECKu80 →+0.311+3.013.022.01931
Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

Cyclin-E2 by LGALS14 expression — UCEC

Box plot of Cyclin-E2 in LGALS14-low vs LGALS14-high samples in UCEC.

Explore this box plot interactively →

Exploration