LGALS13

Across TCGA patient cohorts, LGALS13 protein abundance is significantly associated with the RNA expression of many other genes, with 371 significant associations in total. GBM shows the largest number of these associations.

The most reproducible LGALS13-associated genes across cancer lineages are SLC32A1, BEX4, and PARP4. Each is linked with LGALS13 in more than 1 cancer types. Because this analysis shows association rather than direction, both LGALS13-to-partner and partner-to-LGALS13 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, LGALS13 versus SLC32A1 in GBM, with a Pearson correlation of -0.90.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LGALS13→partner) and Y-score (partner→LGALS13) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	SLC32A1 →	-2.116	-0.693	.001	.001	3	1
GBM	BEX4 →	+1.286	+0.693	.003	.001	3	1
GBM	PARP4 →	+0.796	+0.693	.001	.001	3	1
GBM	ERCC2 →	-0.499	-0.693	.001	.001	3	1
GBM	OAZ1 →	+0.446	+0.693	.007	.001	3	1
GBM	HOXA6 →	-0.513	-0.693	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 371 associations by consensus.

LGALS13 vs SLC32A1 — GBM

Explore this scatter interactively →