LGALS13

Across TCGA patient cohorts, LGALS13 mutation is significantly associated with the RNA expression of many other genes, with 153 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible LGALS13-associated genes across cancer lineages are RN7SL567P, PUDPP1, and PCYT1B-AS1. Each is linked with LGALS13 in more than 2 cancer types. Because this analysis shows association rather than direction, both LGALS13-to-partner and partner-to-LGALS13 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RN7SL567P grouped by LGALS13-low versus LGALS13-high in BLCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LGALS13→partner) and Y-score (partner→LGALS13) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLCA	RN7SL567P →	+0.154	+5.018	<.001	.004	3	3
BLCA	PUDPP1 →	+0.096	+4.497	<.001	.009	3	2
HNSC	PCYT1B-AS1 →	+0.192	+5.655	<.001	.004	3	2
SKCM	ARF4P3 →	+0.052	+3.097	.002	.002	3	2
COAD	EI24P3 →	+0.121	+4.577	.008	.004	3	2
COAD	RPL34P8 →	+0.334	+4.993	<.001	.002	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 153 associations by consensus.

RN7SL567P by LGALS13 expression — BLCA

Explore this box plot interactively →