LGALS13

Across TCGA cell cohorts, LGALS13 RNA expression is significantly associated with the mutation status of many other genes, with 68 significant associations in total. CNS shows the largest number of these associations.

The most reproducible LGALS13-associated genes across cancer lineages are SMARCA4, ZNF536, and KIF26B. Each is linked with LGALS13 in more than 1 cancer types. Because this analysis shows association rather than direction, both LGALS13-to-partner and partner-to-LGALS13 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SMARCA4 grouped by LGALS13-low versus LGALS13-high in PANCREAS.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LGALS13→partner) and Y-score (partner→LGALS13) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	SMARCA4 →	+5.614	+0.060	.002	<.001	3	2
PANCREAS	ZNF536 →	+5.614	+0.060	.002	<.001	3	2
LUNG_NSCLC_LUAD	KIF26B →	+2.362	+0.206	.008	.006	3	2
PANCREAS	BNC1 →	+4.614	+0.045	.004	<.001	3	1
PANCREAS	USP19 →	+4.029	+0.036	.007	<.001	3	1
PANCREAS	LSM1 →	+4.614	+0.045	.004	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 68 associations by consensus.

SMARCA4 by LGALS13 expression — PANCREAS

Explore this box plot interactively →