LGALS1

RNA expression — cross-omics
Cross-omicsRNA → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, LGALS1 RNA expression is significantly associated with the protein abundance of many other proteins, with 20,541 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible LGALS1-associated proteins across cancer lineages are SH3PXD2B, ITGA5, and LOXL2. Each is linked with LGALS1 in more than 8 cancer types. Because this analysis shows association rather than direction, both LGALS1-to-partner and partner-to-LGALS1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, LGALS1 versus SH3PXD2B in OV, with a Pearson correlation of 0.60.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (LGALS1→partner) and Y-score (partner→LGALS1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
OVSH3PXD2B →+0.478+1.055<.001<.00139
OVITGA5 →+0.692+0.947<.001<.00139
LSCCLOXL2 →+0.982+0.986<.001<.00139
CCRCCPLAU →+1.147+1.057.001.00139
OVPLOD2 →+0.931+0.789<.001<.00139
GBMP4HA2 →+0.922+0.906<.001<.00139
Each partner links to its Q-omics profile. Showing the 6 strongest of 20,541 associations by consensus.

LGALS1 vs SH3PXD2B — OV

Per-sample scatter of LGALS1 vs SH3PXD2B in OV (Pearson r = 0.60).

Explore this scatter interactively →

Exploration