LGALS1

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, LGALS1 protein abundance is significantly associated with the RNA expression of many other genes, with 18,999 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible LGALS1-associated genes across cancer lineages are MMP16, CTHRC1, and SYNPO. Each is linked with LGALS1 in more than 8 cancer types. Because this analysis shows association rather than direction, both LGALS1-to-partner and partner-to-LGALS1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, LGALS1 versus MMP16 in HNSC, with a Pearson correlation of 0.53.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LGALS1→partner) and Y-score (partner→LGALS1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
HNSCMMP16 →+1.009+0.431<.001<.00139
OVCTHRC1 →+2.177+0.741<.001<.00139
OVSYNPO →+1.469+0.629<.001.00139
CCRCCGXYLT2 →+1.565+0.488<.001<.00139
UCECBNC2 →+1.374+0.553<.001<.00139
OVVIM →+1.127+0.664<.001<.00139
Each partner links to its Q-omics profile. Showing the 6 strongest of 18,999 associations by consensus.

LGALS1 vs MMP16 — HNSC

Per-sample scatter of LGALS1 vs MMP16 in HNSC (Pearson r = 0.53).

Explore this scatter interactively →

Exploration