LGALS1

Across TCGA cell cohorts, LGALS1 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,958 significant associations in total. BONE shows the largest number of these associations.

The most reproducible LGALS1-associated GO terms across cancer lineages are Negative regulation of cell fate commitment, Negative regulation of T-helper 17 cell lineage commitment, and Collagen fibril organization. Each is linked with LGALS1 in more than 17 cancer types. Because this analysis shows association rather than direction, both LGALS1-to-partner and partner-to-LGALS1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of cell fate commitment grouped by LGALS1-low versus LGALS1-high in LUNG_SCLC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (LGALS1→partner) and Y-score (partner→LGALS1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	Negative regulation of cell fate commitment →	+1.205	+6.463	<.001	<.001	3	18
LUNG_SCLC	Negative regulation of T-helper 17 cell lineage commitment →	+1.194	+4.014	<.001	<.001	3	16
BONE	Collagen fibril organization →	+0.340	+3.730	<.001	<.001	3	16
LIVER	Establishment of epithelial cell apical/basal polarity →	+0.233	+4.298	<.001	<.001	3	16
CNS	Negative regulation of T-helper cell differentiation →	+0.186	+2.491	<.001	.001	3	16
BLOOD_Leukemia	Keratinocyte development →	+0.829	+2.619	<.001	<.001	3	16

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,958 associations by consensus.

Negative regulation of cell fate commitment by LGALS1 expression — LUNG_SCLC

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