LEUTX

Mutation & survival
SurvivalMutationKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, LEUTX Mutation is linked to patient survival in 2 of 34 cancer types, making it a survival-associated LEUTX data layer compared with 10 for mass-spec protein.

The strongest signal is observed in mesothelioma (MESO), where higher LEUTX Mutation is associated with worse disease-free survival. In most high-consensus cancer types, elevated LEUTX expression acts as an unfavorable survival marker.

MESO and UCEC are the cancer types where LEUTX Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
MESODFSMedianII,III,IV0.0390.407<.00112view →
UCECOSMedianIII,IV0.0610.588.01812view →
Pink = unfavorable, green = favorable. Showing the 2 strongest of 2 lineages.

Exploration