LETMD1

Across TCGA patient cohorts, LETMD1 RNA expression is significantly associated with the protein abundance of many other proteins, with 16,071 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible LETMD1-associated proteins across cancer lineages are DDX23, SART3, and MYG1. Each is linked with LETMD1 in more than 6 cancer types. Because this analysis shows association rather than direction, both LETMD1-to-partner and partner-to-LETMD1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, LETMD1 versus DDX23 in LSCC, with a Pearson correlation of 0.64.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (LETMD1→partner) and Y-score (partner→LETMD1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	DDX23 →	+0.268	+0.378	<.001	<.001	3	7
LSCC	SART3 →	+0.245	+0.421	<.001	<.001	3	7
PDAC	MYG1 →	+0.336	+0.366	<.001	<.001	3	6
OV	P4HB →	-0.411	-0.632	.001	<.001	3	5
BRCA	UBTF →	+0.252	+0.402	<.001	.001	3	5
LSCC	CRYBG3_S931 →	-0.623	-0.410	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,071 associations by consensus.

LETMD1 vs DDX23 — LSCC

Explore this scatter interactively →