LETMD1

Across TCGA cell cohorts, LETMD1 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,055 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible LETMD1-associated GO terms across cancer lineages are Co-transcriptional RNA 3'-end processing, cleavage and polyadenylation pathway, mRNA splice site recognition, and Fatty acid beta-oxidation using acyl-CoA dehydrogenase. Each is linked with LETMD1 in more than 12 cancer types. Because this analysis shows association rather than direction, both LETMD1-to-partner and partner-to-LETMD1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Co-transcriptional RNA 3'-end processing, cleavage and polyadenylation pathway grouped by LETMD1-low versus LETMD1-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (LETMD1→partner) and Y-score (partner→LETMD1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Co-transcriptional RNA 3'-end processing, cleavage and polyadenylation pathway →	+0.164	+0.763	<.001	<.001	3	13
URINARY_TRACT	mRNA splice site recognition →	+0.143	+0.943	<.001	.001	3	13
STOMACH	Fatty acid beta-oxidation using acyl-CoA dehydrogenase →	+0.111	+0.662	<.001	<.001	3	12
URINARY_TRACT	Chiasma assembly →	+0.233	+0.789	<.001	<.001	3	12
URINARY_TRACT	Taurine biosynthetic process →	+1.079	+0.666	.001	.008	3	11
URINARY_TRACT	Alkanesulfonate biosynthetic process →	+1.079	+0.666	.001	.008	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,055 associations by consensus.

Co-transcriptional RNA 3'-end processing, cleavage and polyadenylation pathway by LETMD1 expression — BONE

Explore this box plot interactively →