LEPROTL1

Across TCGA patient cohorts, LEPROTL1 RNA expression is significantly associated with the protein abundance of many other proteins, with 11,124 significant associations in total. GBM shows the largest number of these associations.

The most reproducible LEPROTL1-associated proteins across cancer lineages are XPO7, PCM1, and PPP2CB. Each is linked with LEPROTL1 in more than 7 cancer types. Because this analysis shows association rather than direction, both LEPROTL1-to-partner and partner-to-LEPROTL1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, LEPROTL1 versus XPO7 in BRCA, with a Pearson correlation of 0.41.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (LEPROTL1→partner) and Y-score (partner→LEPROTL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	XPO7 →	+0.485	+0.555	<.001	<.001	3	8
BRCA	PCM1 →	+0.808	+0.808	<.001	<.001	3	7
OV	PPP2CB →	+0.513	+0.575	<.001	<.001	3	7
HNSC	CCAR2 →	+0.319	+0.423	<.001	<.001	2	8
BRCA	PPP2R2A →	+0.513	+0.541	<.001	<.001	3	6
BRCA	KIF13B →	+0.652	+0.616	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,124 associations by consensus.

LEPROTL1 vs XPO7 — BRCA

Explore this scatter interactively →