Across TCGA patient cohorts, LEPROT mutation is significantly associated with the immune_cell of many other genes, with 2 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible LEPROT-associated genes across cancer lineages are Endothelial cells and lymphatic Endothelial cells. Each is linked with LEPROT in more than 1 cancer types. Because this analysis shows association rather than direction, both LEPROT-to-partner and partner-to-LEPROT results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LEPROT→partner) and Y-score (partner→LEPROT) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Endothelial cells →	-0.045	-2.991	.040	.036	2	1
UCEC	lymphatic Endothelial cells →	-0.028	-2.946	.041	.037	1	1

Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

Exploration

LEPROT survival (RNA) · tumor vs normal (RNA) · all LEPROT data types