LENG9

Across TCGA patient cohorts, LENG9 RNA expression is significantly associated with the go_rna of many other GO terms, with 7,163 significant associations in total. LGG shows the largest number of these associations.

The most reproducible LENG9-associated GO terms across cancer lineages are tRNA thio-modification, Negative regulation of protein localization to chromatin, and Positive regulation of action potential. Each is linked with LENG9 in more than 19 cancer types. Because this analysis shows association rather than direction, both LENG9-to-partner and partner-to-LENG9 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, tRNA thio-modification grouped by LENG9-low versus LENG9-high in READ.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (LENG9→partner) and Y-score (partner→LENG9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
READ	tRNA thio-modification →	+0.060	+0.541	<.001	<.001	3	20
KICH	Negative regulation of protein localization to chromatin →	+0.049	+0.473	<.001	.004	2	18
ACC	Positive regulation of action potential →	+0.125	+1.327	<.001	<.001	2	17
READ	Free ubiquitin chain polymerization →	+0.043	+0.501	<.001	<.001	3	14
MESO	NLS-bearing protein import into nucleus →	-0.043	-0.656	<.001	.001	3	14
SARC	Regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion →	-0.047	-0.623	<.001	<.001	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,163 associations by consensus.

tRNA thio-modification by LENG9 expression — READ

Explore this box plot interactively →