LENG8

RNA expression — cross-omics
Cross-omicsRNA → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, LENG8 RNA expression is significantly associated with the protein abundance of many other proteins, with 8,030 significant associations in total. GBM shows the largest number of these associations.

The most reproducible LENG8-associated proteins across cancer lineages are AHSA1, DBNL_S283, and LUM. Each is linked with LENG8 in more than 2 cancer types. Because this analysis shows association rather than direction, both LENG8-to-partner and partner-to-LENG8 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, LENG8 versus AHSA1 in BRCA, with a Pearson correlation of -0.32.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (LENG8→partner) and Y-score (partner→LENG8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BRCAAHSA1 →-0.353-0.641<.001.00333
PDACDBNL_S283 →-0.581-0.325.006.00533
OVLUM →+0.710+1.237.001.00233
GBMMINK1_S732 →-0.511-0.555.001<.00133
CCRCCSPAG9_T595 →-0.455-0.392.006.00633
GBMTRIM28 →+0.403+0.563<.001<.00133
Each partner links to its Q-omics profile. Showing the 6 strongest of 8,030 associations by consensus.

LENG8 vs AHSA1 — BRCA

Per-sample scatter of LENG8 vs AHSA1 in BRCA (Pearson r = -0.32).

Explore this scatter interactively →

Exploration