LENG8

Across TCGA patient cohorts, LENG8 protein abundance is significantly associated with the RNA expression of many other genes, with 12,496 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible LENG8-associated genes across cancer lineages are CCT3, DDX11, and UTP6. Each is linked with LENG8 in more than 5 cancer types. Because this analysis shows association rather than direction, both LENG8-to-partner and partner-to-LENG8 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, LENG8 versus CCT3 in HNSC, with a Pearson correlation of 0.23.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LENG8→partner) and Y-score (partner→LENG8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	CCT3 →	+0.770	+0.167	<.001	<.001	3	6
OV	DDX11 →	+0.931	+0.381	<.001	<.001	3	5
HNSC	UTP6 →	+0.548	+0.130	.007	.005	3	5
HNSC	KIF20A →	+1.145	+0.175	<.001	.001	3	5
GBM	HELLS →	+0.944	+0.252	<.001	<.001	3	5
LSCC	DAP3 →	+0.527	+0.177	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,496 associations by consensus.

LENG8 vs CCT3 — HNSC

Explore this scatter interactively →