LENG8

Across TCGA cell cohorts, LENG8 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,442 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible LENG8-associated GO terms across cancer lineages are Cilium or flagellum-dependent cell motility, Cilium-dependent cell motility, and mRNA splice site recognition. Each is linked with LENG8 in more than 17 cancer types. Because this analysis shows association rather than direction, both LENG8-to-partner and partner-to-LENG8 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Cilium or flagellum-dependent cell motility grouped by LENG8-low versus LENG8-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (LENG8→partner) and Y-score (partner→LENG8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Cilium or flagellum-dependent cell motility →	-0.111	-1.740	<.001	<.001	3	18
UPPER_AERODIGESTIVE_TRACT	Cilium-dependent cell motility →	-0.111	-1.740	<.001	<.001	3	18
UPPER_AERODIGESTIVE_TRACT	mRNA splice site recognition →	+0.130	+1.464	<.001	<.001	3	18
UPPER_AERODIGESTIVE_TRACT	Flagellated sperm motility →	-0.118	-1.550	<.001	<.001	3	17
STOMACH	Protein localization to cytoplasmic stress granule →	+0.176	+1.291	<.001	.002	3	17
UPPER_AERODIGESTIVE_TRACT	Cilium movement involved in cell motility →	-0.115	-1.740	<.001	<.001	3	17

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,442 associations by consensus.

Cilium or flagellum-dependent cell motility by LENG8 expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →