LENG1

Across TCGA patient cohorts, LENG1 RNA expression is significantly associated with the protein abundance of many other proteins, with 11,886 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible LENG1-associated proteins across cancer lineages are STRN4, TBRG4, and PRKD2_S710. Each is linked with LENG1 in more than 5 cancer types. Because this analysis shows association rather than direction, both LENG1-to-partner and partner-to-LENG1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, LENG1 versus STRN4 in GBM, with a Pearson correlation of 0.38.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (LENG1→partner) and Y-score (partner→LENG1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	STRN4 →	+0.234	+0.358	<.001	<.001	3	6
BRCA	TBRG4 →	-0.351	-0.612	<.001	<.001	3	5
PDAC	PRKD2_S710 →	+0.648	+0.322	<.001	<.001	3	4
LUAD	GDI1 →	+0.276	+0.269	<.001	.002	3	4
PDAC	CHMP2A →	+0.410	+0.317	.001	<.001	3	4
CCRCC	TBL2 →	-0.468	-0.354	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,886 associations by consensus.

LENG1 vs STRN4 — GBM

Explore this scatter interactively →