LENG1

Across TCGA patient cohorts, LENG1 protein abundance is significantly associated with the RNA expression of many other genes, with 8,866 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible LENG1-associated genes across cancer lineages are MVP, NOL3, and TMEM43. Each is linked with LENG1 in more than 2 cancer types. Because this analysis shows association rather than direction, both LENG1-to-partner and partner-to-LENG1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, LENG1 versus MVP in OV, with a Pearson correlation of -0.28.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LENG1→partner) and Y-score (partner→LENG1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	MVP →	-0.524	-0.392	.002	<.001	3	2
OV	NOL3 →	-0.570	-0.292	.004	.005	3	2
OV	TMEM43 →	-0.390	-0.335	.004	.007	3	2
OV	GXYLT2 →	-0.960	-0.456	.008	.002	3	2
OV	ZNF569 →	+0.607	+0.385	.002	.001	3	2
UCEC	WASL-DT →	-0.553	-0.217	<.001	.002	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,866 associations by consensus.

LENG1 vs MVP — OV

Explore this scatter interactively →