LEMD3

Across TCGA patient cohorts, LEMD3 protein abundance is significantly associated with the RNA expression of many other genes, with 10,571 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible LEMD3-associated genes across cancer lineages are APOBR, ITGB2-AS1, and MILR1. Each is linked with LEMD3 in more than 4 cancer types. Because this analysis shows association rather than direction, both LEMD3-to-partner and partner-to-LEMD3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, LEMD3 versus APOBR in GBM, with a Pearson correlation of -0.33.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LEMD3→partner) and Y-score (partner→LEMD3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	APOBR →	-0.682	-0.184	<.001	<.001	3	5
LUAD	ITGB2-AS1 →	-0.748	-0.230	.008	.002	3	5
UCEC	MILR1 →	-0.969	-0.442	<.001	<.001	3	4
GBM	CYTH4 →	-0.858	-0.191	<.001	<.001	3	4
GBM	NCF4 →	-0.856	-0.197	<.001	<.001	3	4
UCEC	RASAL3 →	-0.613	-0.257	<.001	.003	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,571 associations by consensus.

LEMD3 vs APOBR — GBM

Explore this scatter interactively →