Across TCGA patient cohorts, LEMD1 RNA expression is significantly associated with the protein abundance of many other proteins, with 13,479 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible LEMD1-associated proteins across cancer lineages are SERPINB1, CDK18, and LAD1. Each is linked with LEMD1 in more than 4 cancer types. Because this analysis shows association rather than direction, both LEMD1-to-partner and partner-to-LEMD1 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (LEMD1→partner) and Y-score (partner→LEMD1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	SERPINB1 →	+0.369	+0.857	<.001	.001	3	5
BRCA	CDK18 →	+0.424	+1.162	<.001	<.001	3	5
BRCA	LAD1 →	+0.777	+1.350	<.001	<.001	3	4
LUAD	LAD1_S177 →	+0.733	+0.904	<.001	<.001	3	4
BRCA	PFKP →	+0.679	+1.143	<.001	<.001	3	4
BRCA	MPHOSPH10 →	+0.423	+2.002	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,479 associations by consensus.

Exploration

LEMD1 survival (RNA) · tumor vs normal (RNA) · all LEMD1 data types