Across TCGA patient cohorts, LEKR1 RNA expression is significantly associated with the protein abundance of many other proteins, with 12,551 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible LEKR1-associated proteins across cancer lineages are MLF1_S34, IFT46, and ZNF638. Each is linked with LEKR1 in more than 4 cancer types. Because this analysis shows association rather than direction, both LEKR1-to-partner and partner-to-LEKR1 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (LEKR1→partner) and Y-score (partner→LEKR1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	MLF1_S34 →	+1.125	+0.634	.001	.002	3	5
OV	IFT46 →	+0.543	+0.584	.001	<.001	3	5
HNSC	ZNF638 →	+0.297	+0.508	<.001	.008	3	5
BRCA	LZTFL1 →	+0.620	+0.352	<.001	<.001	3	5
BRCA	TRAF3IP1 →	+0.352	+0.293	<.001	<.001	3	5
BRCA	TTC26 →	+0.324	+0.336	<.001	.003	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,551 associations by consensus.

Exploration

LEKR1 survival (RNA) · tumor vs normal (RNA) · all LEKR1 data types