Across TCGA cell cohorts, LEKR1 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,954 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible LEKR1-associated GO terms across cancer lineages are Embryonic neurocranium morphogenesis, Positive regulation of neurotrophin TRK receptor signaling pathway, and Establishment of protein localization to membrane. Each is linked with LEKR1 in more than 7 cancer types. Because this analysis shows association rather than direction, both LEKR1-to-partner and partner-to-LEKR1 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (LEKR1→partner) and Y-score (partner→LEKR1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	Embryonic neurocranium morphogenesis →	-0.147	-1.078	.007	.001	2	8
SOFT_TISSUE	Positive regulation of neurotrophin TRK receptor signaling pathway →	-0.215	-0.453	<.001	<.001	3	7
SOFT_TISSUE	Establishment of protein localization to membrane →	+0.048	+0.571	<.001	<.001	3	7
OVARY	Alternative mRNA splicing, via spliceosome →	+0.085	+0.640	.001	.006	3	7
OVARY	Adenylate cyclase-modulating G protein-coupled receptor signaling pathway →	-0.045	-0.689	.006	.008	3	7
SOFT_TISSUE	Indole-containing compound catabolic process →	-0.186	-0.446	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,954 associations by consensus.

Exploration

LEKR1 survival (RNA) · tumor vs normal (RNA) · all LEKR1 data types