Across TCGA cell cohorts, LEKR1 mutation is significantly associated with the mutation status of many other genes, with 706 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible LEKR1-associated genes across cancer lineages are CAPN14, C1orf68, and TIGD6. Each is linked with LEKR1 in more than 2 cancer types. Because this analysis shows association rather than direction, both LEKR1-to-partner and partner-to-LEKR1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LEKR1→partner) and Y-score (partner→LEKR1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	CAPN14 →	+3.339	+4.662	.003	.003	1	3
BLOOD_Leukemia	C1orf68 →	+4.894	+4.894	.004	.004	1	3
BLOOD_Leukemia	TIGD6 →	+5.894	+5.321	.002	.002	1	3
BLOOD_Leukemia	OR2M2 →	+5.894	+5.321	.002	.002	1	3
LUNG_NSCLC_LUAD	NXF3 →	+4.339	+4.339	.009	.009	1	3
LUNG_NSCLC_LUAD	HLA-C →	+5.339	+4.772	.004	.004	1	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 706 associations by consensus.

Exploration

LEKR1 survival (RNA) · tumor vs normal (RNA) · all LEKR1 data types