LECT2

Across TCGA cell cohorts, LECT2 RNA expression is significantly associated with the RNA expression of many other genes, with 1,728 significant associations in total. UPPER_AERODIGESTIVE_TRACT shows the largest number of these associations.

The most reproducible LECT2-associated genes across cancer lineages are FBXL21P, NKX2-4, and OR2W3. Each is linked with LECT2 in more than 11 cancer types. Because this analysis shows association rather than direction, both LECT2-to-partner and partner-to-LECT2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, LECT2 versus FBXL21P in LIVER, with a Pearson correlation of 0.93.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LECT2→partner) and Y-score (partner→LECT2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIVER	FBXL21P →	+3.990	+1.156	<.001	<.001	3	12
BLOOD_Lymphoma	NKX2-4 →	+0.535	+0.394	<.001	.004	3	3
SKIN	OR2W3 →	+1.273	+0.110	<.001	.006	2	3
BREAST	CCDC42 →	+0.213	+0.168	.003	.005	3	2
URINARY_TRACT	CCL11 →	+0.014	+0.923	<.001	<.001	3	2
URINARY_TRACT	OR4F5 →	+0.025	+0.770	.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,728 associations by consensus.

LECT2 vs FBXL21P — LIVER

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