LECT2

Across TCGA cell cohorts, LECT2 RNA expression is significantly associated with the go_rna of many other GO terms, with 548 significant associations in total. OVARY shows the largest number of these associations.

The most reproducible LECT2-associated GO terms across cancer lineages are RNA modification, Methylation, and Calcium ion transmembrane transport. Each is linked with LECT2 in more than 4 cancer types. Because this analysis shows association rather than direction, both LECT2-to-partner and partner-to-LECT2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA modification grouped by LECT2-low versus LECT2-high in CNS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (LECT2→partner) and Y-score (partner→LECT2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CNS	RNA modification →	+0.033	+0.271	<.001	.008	3	4
LUNG_SCLC	Methylation →	+0.038	+0.139	.001	.008	3	4
SKIN	Calcium ion transmembrane transport →	-0.052	-0.133	<.001	.002	2	5
UPPER_AERODIGESTIVE_TRACT	Positive regulation of DNA-templated transcription, elongation →	+0.067	+0.016	.006	.009	3	4
UPPER_AERODIGESTIVE_TRACT	Positive regulation of translation →	+0.059	+0.016	.008	.009	3	4
UPPER_AERODIGESTIVE_TRACT	Gephyrin clustering involved in postsynaptic density assembly →	-0.249	-0.024	<.001	.007	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 548 associations by consensus.

RNA modification by LECT2 expression — CNS

Explore this box plot interactively →