Across TCGA patient cohorts, LDOC1 mutation is significantly associated with the total protein of many other genes, with 24 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible LDOC1-associated genes across cancer lineages are Stathmin, eIF4E, and INPP4B. Each is linked with LDOC1 in more than 1 cancer types. Because this analysis shows association rather than direction, both LDOC1-to-partner and partner-to-LDOC1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LDOC1→partner) and Y-score (partner→LDOC1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	Stathmin →	+0.264	+2.820	.001	.035	3	1
UCEC	eIF4E →	+0.185	+2.392	.012	<.001	3	1
UCEC	INPP4B →	-0.258	-1.700	.024	.042	3	1
UCEC	JNK2 →	+0.239	+2.348	<.001	.018	3	1
UCEC	MEK1 →	+0.345	+2.222	.007	.010	3	1
UCEC	Myosin-IIa →	+0.149	+1.595	.029	.042	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 24 associations by consensus.

Exploration

LDOC1 survival (RNA) · tumor vs normal (RNA) · all LDOC1 data types