Across TCGA cell cohorts, LDOC1 mutation is significantly associated with the RNA expression of many other genes, with 7 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible LDOC1-associated genes across cancer lineages are MMP26, OR10K1, and TAFA1. Each is linked with LDOC1 in more than 1 cancer types. Because this analysis shows association rather than direction, both LDOC1-to-partner and partner-to-LDOC1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LDOC1→partner) and Y-score (partner→LDOC1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	MMP26 →	+0.027	+3.217	.002	.006	3	1
LARGE_INTESTINE	OR10K1 →	+0.002	+3.700	<.001	.009	3	1
LARGE_INTESTINE	TAFA1 →	+0.239	+3.103	.001	.004	3	1
LARGE_INTESTINE	MINAR2 →	+0.031	+3.297	.001	.002	3	1
LARGE_INTESTINE	DAZ2 →	+0.145	+4.000	.002	<.001	3	1
LARGE_INTESTINE	RBMY1J →	+0.005	+3.700	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 7 associations by consensus.

Exploration

LDOC1 survival (RNA) · tumor vs normal (RNA) · all LDOC1 data types