LDLRAD4

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, LDLRAD4 mutation is significantly associated with the RNA expression of many other genes, with 1 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible LDLRAD4-associated genes across cancer lineages are REG3G. Each is linked with LDLRAD4 in more than 1 cancer types. Because this analysis shows association rather than direction, both LDLRAD4-to-partner and partner-to-LDLRAD4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, REG3G grouped by LDLRAD4-low versus LDLRAD4-high in BLOOD_Lymphoma.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LDLRAD4→partner) and Y-score (partner→LDLRAD4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BLOOD_LymphomaREG3G →+0.026+4.867.004.00931
Each partner links to its Q-omics profile. Showing the 1 strongest of 1 associations by consensus.

REG3G by LDLRAD4 expression — BLOOD_Lymphoma

Box plot of REG3G in LDLRAD4-low vs LDLRAD4-high samples in BLOOD_Lymphoma.

Explore this box plot interactively →

Exploration