LDLRAD2

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, LDLRAD2 mutation is significantly associated with the RNA expression of many other genes, with 824 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible LDLRAD2-associated genes across cancer lineages are RNU6-912P, CPLX3, and ARHGAP26-IT1. Each is linked with LDLRAD2 in more than 1 cancer types. Because this analysis shows association rather than direction, both LDLRAD2-to-partner and partner-to-LDLRAD2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LDLRAD2→partner) and Y-score (partner→LDLRAD2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
CESCRNU6-912P →+0.358+5.010<.001.00932
CESCCPLX3 →+0.022+6.342<.001.00132
HNSCARHGAP26-IT1 →+0.207+4.161<.001.00432
HNSCRNA5SP503 →+0.265+4.883<.001.00432
UCECZDHHC20P1 →+0.315+2.957<.001.00232
COADRN7SL89P →+0.204+5.020.006<.00132
Each partner links to its Q-omics profile. Showing the 6 strongest of 824 associations by consensus.

Exploration