Across TCGA cell cohorts, LDLRAD2 mutation is significantly associated with the RNA expression of many other genes, with 9 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible LDLRAD2-associated genes across cancer lineages are CFHR2, PNMA3, and BPIFA1. Each is linked with LDLRAD2 in more than 1 cancer types. Because this analysis shows association rather than direction, both LDLRAD2-to-partner and partner-to-LDLRAD2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LDLRAD2→partner) and Y-score (partner→LDLRAD2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	CFHR2 →	+0.257	+5.539	<.001	.003	3	1
LARGE_INTESTINE	PNMA3 →	+0.194	+2.781	<.001	.009	3	1
LARGE_INTESTINE	BPIFA1 →	+0.174	+3.103	<.001	.004	3	1
LARGE_INTESTINE	PRAMEF20 →	+0.008	+3.700	<.001	.009	3	1
LARGE_INTESTINE	C16orf96 →	+0.519	+3.520	.003	.005	3	1
LARGE_INTESTINE	CENPVL1 →	+0.127	+2.925	.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 9 associations by consensus.

Exploration

LDLRAD2 survival (RNA) · tumor vs normal (RNA) · all LDLRAD2 data types