Across TCGA pan-cancer cohorts, LDLRAD1 Mutation is linked to patient survival in 3 of 34 cancer types, making it a survival-associated LDLRAD1 data layer compared with 20 for mass-spec protein and 2 for mass-spec protein.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher LDLRAD1 Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated LDLRAD1 expression acts as an unfavorable survival marker.

KIRC, SKCM, and LIHC are the cancer types where LDLRAD1 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRC	OS	Median	All	0.133	0.805	<.001	42	view →
SKCM	DFS	Median	All	0.362	0.624	.008	15	view →
LIHC	DFS	Median	All	0.092	0.553	.018	3	view →

Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

Exploration

Same gene, other analysis: LDLRAD1 tumor-vs-normal RNA expression · all LDLRAD1 data types