LDHB

RNA expression — cross-omics
Cross-omicsRNA → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, LDHB RNA expression is significantly associated with the protein abundance of many other proteins, with 13,723 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible LDHB-associated proteins across cancer lineages are NCAPG_S674, NIP7, and BYSL. Each is linked with LDHB in more than 5 cancer types. Because this analysis shows association rather than direction, both LDHB-to-partner and partner-to-LDHB results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, LDHB versus NCAPG_S674 in UCEC, with a Pearson correlation of 0.37.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (LDHB→partner) and Y-score (partner→LDHB) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECNCAPG_S674 →+0.807+0.734.001<.00136
BRCANIP7 →+0.429+0.800<.001<.00136
BRCABYSL →+0.303+1.108.002<.00136
BRCAEMG1 →+0.334+0.784<.001<.00136
LSCCMCM4 →+0.677+0.841<.001<.00136
LSCCMCM6 →+0.665+0.828<.001<.00136
Each partner links to its Q-omics profile. Showing the 6 strongest of 13,723 associations by consensus.

LDHB vs NCAPG_S674 — UCEC

Per-sample scatter of LDHB vs NCAPG_S674 in UCEC (Pearson r = 0.37).

Explore this scatter interactively →

Exploration