LDHB

Across TCGA patient cohorts, LDHB protein abundance is significantly associated with the RNA expression of many other genes, with 17,523 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible LDHB-associated genes across cancer lineages are LDHBP2, MAGOHB, and MRPL51. Each is linked with LDHB in more than 5 cancer types. Because this analysis shows association rather than direction, both LDHB-to-partner and partner-to-LDHB results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, LDHB versus LDHBP2 in OV, with a Pearson correlation of 0.54.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LDHB→partner) and Y-score (partner→LDHB) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	LDHBP2 →	+1.621	+0.955	<.001	<.001	3	6
OV	MAGOHB →	+0.733	+0.822	<.001	<.001	3	5
OV	MRPL51 →	+0.697	+0.516	<.001	<.001	3	4
BRCA	TPI1 →	+0.685	+0.591	.001	.006	3	4
OV	GOLT1B →	+0.852	+0.756	<.001	<.001	3	4
OV	CMAS →	+0.694	+0.513	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 17,523 associations by consensus.

LDHB vs LDHBP2 — OV

Explore this scatter interactively →