LDHAP7

Across TCGA pan-cancer cohorts, LDHAP7 RNA differs between tumor and matched normal tissue in 9 of 18 cancer types tested, making tumor–normal expression one of LDHAP7’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where LDHAP7 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types LDHAP7 is over-expressed in tumor, although a few such as KICH show the opposite, repressed pattern.

KIRC, LUAD, and HNSC are the cancer types where LDHAP7 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in LDHAP7 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRC	Male	All	+1.553	<.001	8	view →
LUAD	All	II,III,IV	+1.061	<.001	7	view →
HNSC	All	All	+0.693	.006	7	view →
LUSC	Male	All	+1.060	<.001	6	view →
BRCA	All	All	+0.379	.001	4	view →
KIRP	All	II,III,IV	+0.893	.006	2	view →
COAD	All	II,III,IV	+0.618	.011	2	view →
UCEC	All	All	+0.600	.023	2	view →
KICH	All	All	−0.520	.048	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 9 strongest of 9 lineages.

LDHAP7–KIRC

Open the KIRC breakdown →