LDHAP3

Across TCGA pan-cancer cohorts, LDHAP3 RNA differs between tumor and matched normal tissue in 9 of 18 cancer types tested, making tumor–normal expression one of LDHAP3’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where LDHAP3 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types LDHAP3 is over-expressed in tumor.

KIRC, LUAD, and HNSC are the cancer types where LDHAP3 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in LDHAP3 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRC	Male	All	+1.173	<.001	11	view →
LUAD	All	II,III,IV	+0.761	<.001	8	view →
HNSC	All	All	+0.734	<.001	8	view →
KIRP	All	II,III,IV	+0.926	.001	7	view →
BRCA	All	II,III,IV	+0.263	<.001	6	view →
LUSC	All	All	+0.803	<.001	5	view →
CHOL	All	II,III,IV	+0.624	.018	2	view →
UCEC	All	All	+0.563	.013	2	view →
COAD	Female	IV	+0.105	.011	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 9 strongest of 9 lineages.

LDHAP3–KIRC

Open the KIRC breakdown →