LDHAP2

Across TCGA pan-cancer cohorts, LDHAP2 RNA is linked to patient survival in 25 of 34 cancer types, making it the most broadly survival-associated LDHAP2 data layer.

The strongest signal is observed in adrenocortical carcinoma (ACC), where higher LDHAP2 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated LDHAP2 expression acts as an unfavorable survival marker, although some lineages such as LAML and BRCA show a favorable association.

ACC, KIRC, and KICH are the cancer types where LDHAP2 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
ACC	DFS	Quartile	All	0.203	0.663	<.001	63	view →
KIRC	DFS	Tertile	All	0.538	0.665	.001	54	view →
KICH	DFS	Tertile	III,IV	0.298	0.913	.005	47	view →
LGG	OS	Median	All	0.849	0.940	<.001	41	view →
LAML	DFS	Tertile	All	0.639	0.251	<.001	36	view →
MESO	OS	Tertile	III,IV	0.178	0.732	.006	27	view →
SARC	DFS	Median	All	0.227	0.448	<.001	25	view →
BRCA	OS	Median	II,III,IV	0.971	0.943	.006	22	view →
LIHC	DFS	Tertile	All	0.454	0.616	.003	21	view →
KIRP	DFS	Median	All	0.797	0.906	.004	19	view →
READ	DFS	Median	III,IV	0.782	0.379	.016	16	view →
SKCM	OS	Quartile	III,IV	0.434	0.200	.005	13	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 25 lineages.

LDHAP2–ACC (DFS)

Open the ACC breakdown →