LDB2

Across TCGA patient cohorts, LDB2 protein abundance is significantly associated with the RNA expression of many other genes, with 5,740 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible LDB2-associated genes across cancer lineages are RASL12, MEIS3, and ACTA2. Each is linked with LDB2 in more than 2 cancer types. Because this analysis shows association rather than direction, both LDB2-to-partner and partner-to-LDB2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, LDB2 versus RASL12 in CCRCC, with a Pearson correlation of 0.89.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LDB2→partner) and Y-score (partner→LDB2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	RASL12 →	+2.403	+1.233	<.001	<.001	3	3
UCEC	MEIS3 →	+0.940	+0.573	<.001	<.001	3	3
UCEC	ACTA2 →	+1.772	+0.736	<.001	<.001	3	3
CCRCC	CNRIP1 →	+1.534	+0.959	.002	.003	3	3
CCRCC	HSPA12B →	+1.812	+0.938	<.001	.001	3	3
BRCA	USP37 →	-1.338	-1.041	.001	.002	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,740 associations by consensus.

LDB2 vs RASL12 — CCRCC

Explore this scatter interactively →