LDB2

Across TCGA patient cohorts, LDB2 protein abundance is significantly associated with the protein abundance of many other proteins, with 13,045 significant associations in total. GBM shows the largest number of these associations.

The most reproducible LDB2-associated proteins across cancer lineages are ERG, SNRK, and TECPR2. Each is linked with LDB2 in more than 3 cancer types. Because this analysis shows association rather than direction, both LDB2-to-partner and partner-to-LDB2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, LDB2 versus ERG in CCRCC, with a Pearson correlation of 0.85.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (LDB2→partner) and Y-score (partner→LDB2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	ERG →	+0.701	+0.864	<.001	.001	3	4
CCRCC	SNRK →	+0.585	+0.814	<.001	.002	3	4
CCRCC	TECPR2 →	+0.703	+1.133	.004	.001	3	4
UCEC	HSPG2 →	+0.765	+0.697	<.001	<.001	3	3
CCRCC	IQSEC1 →	+0.451	+0.881	<.001	.002	3	3
UCEC	JCAD_S1044 →	+0.801	+0.553	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,045 associations by consensus.

LDB2 vs ERG — CCRCC

Explore this scatter interactively →