LDB2

Across TCGA cell cohorts, LDB2 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,327 significant associations in total. BONE shows the largest number of these associations.

The most reproducible LDB2-associated GO terms across cancer lineages are RNA localization, Negative regulation of microtubule depolymerization, and Ionotropic glutamate receptor signaling pathway. Each is linked with LDB2 in more than 5 cancer types. Because this analysis shows association rather than direction, both LDB2-to-partner and partner-to-LDB2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA localization grouped by LDB2-low versus LDB2-high in URINARY_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (LDB2→partner) and Y-score (partner→LDB2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	RNA localization →	+0.052	+0.078	.008	.001	2	6
OVARY	Negative regulation of microtubule depolymerization →	+0.065	+0.181	.005	.006	3	4
KIDNEY	Ionotropic glutamate receptor signaling pathway →	-0.080	-0.124	.008	.008	3	4
SOFT_TISSUE	Negative regulation of calcium ion import across plasma membrane →	+0.181	+1.286	<.001	.008	3	3
BONE	Positive regulation of fever generation →	+1.918	+3.695	<.001	<.001	3	3
KIDNEY	Positive regulation of intracellular protein transport →	+0.057	+0.221	.002	.006	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,327 associations by consensus.

RNA localization by LDB2 expression — URINARY_TRACT

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