Across TCGA cell cohorts, LDB1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,898 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible LDB1-associated GO terms across cancer lineages are Viral translational termination-reinitiation, Positive regulation of intracellular steroid hormone receptor signaling pathway, and Regulation of sister chromatid cohesion. Each is linked with LDB1 in more than 15 cancer types. Because this analysis shows association rather than direction, both LDB1-to-partner and partner-to-LDB1 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (LDB1→partner) and Y-score (partner→LDB1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	Viral translational termination-reinitiation →	+0.101	+0.971	<.001	<.001	3	16
BREAST	Positive regulation of intracellular steroid hormone receptor signaling pathway →	+0.154	+1.227	<.001	<.001	3	15
SOFT_TISSUE	Regulation of sister chromatid cohesion →	+0.117	+0.741	<.001	.004	3	14
SOFT_TISSUE	Regulation of smoothened signaling pathway →	+0.053	+1.177	<.001	<.001	3	14
STOMACH	Pre-mRNA catabolic process →	+0.168	+1.172	<.001	.002	2	15
BONE	Regulation of double-strand break repair →	+0.070	+0.922	.001	.005	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,898 associations by consensus.

Exploration

LDB1 survival (RNA) · tumor vs normal (RNA) · all LDB1 data types